Despite qualification into the next phase of the Leasing.com Trophy now being out of the equation, Sol Campbell does not see Wednesday night’s game as a dead rubber.
Southend lost their first two matches in the competition to Leyton Orient and Brighton U21s and they welcome the AFC Wimledodon in their final group game tomorrow night.
Campbell says he wants to see a performance from his side, no matter what the result is after 90 minutes.
"It means a lot to us,” he said.
"It's all about getting a performance out of the lads. After the last game we need a good performance.
"We need to take the handbrake off. Yes it's hard to do that when you've lost a lot of games, but we've got to start mentally preparing for the league games.
"I'm not saying this is a free hit [against AFC Wimbledon] but it's a game we need to be free in, work hard, want to score goals, want to defend, want to enjoy the challenge.
"The main thing is be free, have passion and do the basics right.
"We need a performance. We need to start approaching games in a good mentality. We have to start well, prepare well - which we do - and start performing as individuals and as a team.
"We're working hard in training, and we need to transfer that onto the pitch."
Campbell will be without Jason Demetriou who has been called up to international duty with Cyprus.
Elsewhere from the squad that lost to Dover, Harry Lennon will not be considered due to disciplinary reasons and Joe Shaughnessy is ruled out for at least a month with a knee injury.
The Blues boss is expected to make some changes to his side, but won’t be making wholesale adjustments.
"There will be a few youngsters [in the side] and some will be on the bench," Campbell added. "A mixture really.
"It's good for the [young] lads to experience that type of pressure."