Southend failed to back up their victory against Bradford as they fell to a 2-0 defeat away at Luton Town thanks to goals from Elliot Lee and a Danny Hylton penalty.
The Hatters, who were in search of their first win since returning to League One, took the lead inside two minutes after Pelly-Ruddock Mpanzu’s effort deflected kindly to Lee to smash home.
Blues responded well but were dominating possession without creating chances and they fell further behind before the interval when Hylton converted from the penalty spot after a foul on Lee.
Chris Powell brought on Theo Robinson and Shawn McCoulsky early in the second-half to try and manufacturer a comeback but it was to no avail with Luton looking the most likely to score again.
Mark Oxley had to make superb one-on-one stops to prevent efforts from Hylton and Andrew Shinnie extending the Hatters lead but they’d already done enough to claim the three points.
Defeat for Blues extended a miserable record for Southend at Kenilworth Road, having not won on any of their last 13 visits, with Blues’ winless run in Bedfordshire dating back to 1964.