The odds ahead of the clash against U's at Roots Hall in Sky Bet League Two.
Cambridge have won just one in ten Sky Bet League Two matches since going out of the FA Cup to Manchester United and are still not quite safe yet (though they are a massive 28/1 for the drop, suggesting that the League sponsors don’t see them as being in any danger).
The U’s are 4/1 to win this win at Southend, who can be backed at 7/10 with the draw 5/2.
The hosts have lost just one of their last ten at Roots Hall as they continue to look to cement a spot in the play-offs – the Blues are quoted at 11/8 for promotion.
There have been four draws in that run, though, while Cambridge have drawn three of their last six, so another sharing of the points could be on the cards.